Do not take ALPRIM if you are allergic to any other medicines containing trimethoprim or any of the ingredients listed at the end of this leaflet. Do not take ALPRIM if you have: a severe blood disorder or anaemia severe kidney problems. Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives. There is the possibility of megaloblastic anaemia developing in patients prescribed trimethoprim whilst taking pyrimethamine for malarial prophylaxis. ALPRIM is available only with a doctor's prescription. The above list includes serious side effects which may require medical attention. If your doctor tells you to stop taking Alprim, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over. If you have not told your doctor about any of the above, tell him/her before you start Alprim tablets contain the following inactive ingredients: lactose monohydrate, povidone, sodium starch glycollate, purified talc and magnesium stearate. Sometimes they are serious, most of the time they are not. effects in some people. Follow the directions on your prescription label carefully, and ask your pharmacist or doctor to explain any part you do not understand. Improving clinical practice and health outcomes for Australia. An independent peer-reviewed journal providing critical commentary on drugs and therapeutics. If your child is age 6 months or older, ibuprofen (Advil, Motrin, others) is OK, too. Tell your doctor if you have, or have had, any medical conditions, especially the following: Your doctor may want to take special care if you have any of these conditions. Alprim may causes insomnia with other common side effects. Some medicines may be affected by ALPRIM, or may affect how well it works. doctor about the risks and benefits of taking ALPRIM during pregnancy. Alprim belongs to a group of medicines called antibiotics. acetaminophen Alcohol (Ethanol) Major Drug Interaction. to be careful with or avoid while taking ALPRIM. You may not experience any of them. NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. These include: Your doctor can tell you what to do if you are taking any of these medicines. 21st ed. These people may include the elderly, people with folate deficiency and people taking certain medicines. See your doctor immediately or go to Accident and Emergency at the nearest hospital if you notice any of the following: The side effects listed above are rare but serious and require urgent medical attention or hospitalisation. Fever. aspirin, acetaminophen, ibuprofen, tramadol, cyclobenzaprine, naproxen, Paracetamol, diclofenac, Tylenol, oxycodone. Follow all directions given to you by your doctor and pharmacist carefully. or hospitalisation. Do not take any other medicines while you are taking ALPRIM without first telling Do not stop taking ALPRIM, even if you feel better after a few days, unless advised by your doctor. Do not take a double dose to make up for the dose you missed. Taking ALPRIM with food will help reduce the chance of a stomach upset. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Do not store ALPRIM or any other medicine in the bathroom or near a sink. Alprim used to treat and prevent urinary tract infections, such as cystitis. This leaflet answers some common questions about ALPRIM. For children 6 to 12 years, the usual dose is half a tablet daily. Taking a double dose greatly increases the risk of side effects. Renal failure is not a recognised side effect of Alprim, although manufacturers advise caution when treating elderly people and people with impaired renal function. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking ALPRIM. For patients with a creatinine clearance of 15 to 30 ml/min, the dose should be 50 mg every 12 hours Patients with severely impaired renal function (creatinine clearance less than 10 mL/min) should not be prescribed Alprim unless the plasma concentration of trimethoprim is monitored repeatedly during treatment. All medicines can have side effects. If your symptoms do not improve within a few days, or if they become worse, tell your Common side effects of Alprim are include: Diarrhea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache may occur. proarrhythmic effects. Alprim passes into breast milk and may affect your baby. If you are not sure what to do or have any questions, ask your doctor or pharmacist. Acetaminophen (Tylenol) can be used as an alternative, but it comes with the risk of increasing the effect of blood thinners. Some of the symptoms of an allergic reaction may include red, itchy skin rashes, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath. If you do not understand the instructions on the pack, ask your doctor or pharmacist. If you take this medicine after the expiry date, it may not work as well. If you are taking single symptom medications, in general, it is OK to take several . or anyone else may have taken too much ALPRIM. For children 6 to 12 years, the usual dose is half a tablet daily. ALPRIM tablets are best taken before bedtime. If you are not sure whether you are taking any of these medicines, check with your A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. [. These people may include the elderly, people with folate deficiency and people taking certain medicines. Heat and dampness can destroy some medicines. Enter other medications to view a detailed report. Check with your doctor as soon as possible if you have any problems while taking ALPRIM even if you do not think the problems are connected with the medicine or are not listed in this leaflet. Ask your doctor if you have any questions about why Alprim has been prescribed for you. There is a problem with The use of trimethoprim in patients with a creatinine clearance of less than 15 ml/min is not recommended. ALPRIM is used to treat infections of the urinary tract caused by bacteria. For children 6 to 12 years, the usual dose is half a tablet daily. the other. Aspirin and acetaminophen relieve pain by keeping your body from making certain natural substances. severe rash with skin peeling, fever, chills and aching muscles. These recommendations are for people who are generally healthy for instance, those who are not immunocompromised or taking chemotherapy drugs and haven't recently had surgery. You may need medical treatment if you get some of the side effects. Read our full disclaimer. Accessed April 8, 2020. The active ingredient in ALPRIM is trimethoprim. Call the doctor if your child seems unusually irritable, lethargic or uncomfortable. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Do not give Alprim to anyone else, even if they have the same condition as you. Do not take ALPRIM after the expiry date (EXP) printed on the pack. Temperature regulation and the pathogenesis of fever. 30-34 Hickson Road They may differ from the information contained in this leaflet. There is no information concerning the right dose for children under the age of 6 years. 11 26), or go to Accident and Emergency at the nearest hospital, if you think you Do not take any other medicines while you are taking ALPRIM without first telling your doctor. following: Your doctor may want to take special care if you have any of these conditions. Follow all directions given to you by your doctor and pharmacist carefully. More info. Making safe and wise decisions for biological disease-modifying antirheumatic drugs (bDMARDs) and other specialised medicines. This can cause serious side effects that affect your liver. information submitted for this request. Add In children, the dosage is also based on their weight. Overdose symptoms may include nausea, vomiting, headache, dizziness, confusion, depression, fever, chills, or flu-like symptoms. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Overdose can occur slowly over a long period of time if your daily doses are too high. The more medicines you take, the more difficult it can be to remember important information about them. Ask your doctor if you have any questions about why ALPRIM has been prescribed for you. Reasonable care is taken to provide accurate information at the time of creation. Talk to your doctor about the need for additional contraception while taking ALPRIM. ALPRIM is a 9.5 mm white normal convex tablet marked "TM/300" on one side, "G" on Encourage your child to rest and drink plenty of fluids. Your infection may not clear completely if you stop taking your medicine too soon. Resistance to both trimethoprim (Alrpim) and cephalexin ( Keflex) isn't rare, especially after repeated treatmnt. Use WebMD's Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in question. Panadol Osteo (acetaminophen), along with signs of an allergic reaction such as itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath, pink or red itchy spots on the skin which may blister and progress to form raised, red, pale-centred marks, redness, blistering, peeling or loosening of skin; bleeding of the lips, eyes, mouth, nose and genitals. You may not experience any of them. ALPRIM. Give your child acetaminophen (Tylenol, others). Independent peer-reviewed journal providing critical commentary on drugs and therapeutics for health professionals, Provides health professionals with timely, independent and evidence-based information, Our new and ongoing programs for healthcare professionals. Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. If your symptoms do not improve within a few days, or if they become worse, tell your doctor. Your doctor has weighed the risks of you taking ALPRIM against the benefits expected for you. Do not take ALPRIM after the expiry date (EXP) printed on the pack. If it is almost time for your next dose, skip the dose you missed and take your next Some of the symptoms of an allergic reaction may include red, itchy skin rashes, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath. Tell your doctor if you are pregnant or plan to become pregnant. In Australia, any unused medicine or waste material should be disposed of by taking it to your local pharmacy. An acetaminophen overdose can damage your liver or cause death. ALPRIM is not recommended for use in children under 6 years of age, as the safety Advertising revenue supports our not-for-profit mission. Do not take ALPRIM if you are allergic to any other medicines containing trimethoprim or any of the ingredients listed at the end of this leaflet. Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much ALPRIM. Yes, getting a Covid-19 vaccine these days can be a bit of a pain, in more ways than one. It's usually not necessary to lower a fever - an elevated temperature is meant to help your body fight off the virus. All medicines have benefits and risks. ALPRIM is rated in Australia as a Category B3 drug for use in pregnancy. Tell your doctor if you are breastfeeding or wish to breastfeed. the unsubscribe link in the e-mail. Do not drive or operate machinery until you know how ALPRIM affects you. can check on your progress. This list is not exhaustive. While taking antibiotics, a person can manage pain with OTC pain relievers such as ibuprofen (Advil) and acetaminophen (Tylenol). Do this even if there are no signs of discomfort or poisoning. Schmitt BD. information and will only use or disclose that information as set forth in our notice of There are 110 drugs known to interact with Panadol Osteo (acetaminophen), along with 3 disease interactions, and 1 alcohol/food interaction. Minimally clinically significant. Tell your doctor if you are pregnant or plan to become pregnant. Haleon, the company behind Panadol, recently launched PanaNatra, a line of non-paracetamol-based pain relief medication. the chance of a stomach upset. This is not a complete list of all possible side effects. Take Alprim on an empty stomach, 1 hour before or 2 hours after meals. The dosage is based on your medical condition and response to treatment. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Avoid giving aspirin to children or teenagers. How do COVID-19 antibody tests differ from diagnostic tests?
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